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Polymorphisms of glutathione S-transferase and methylenetetrahydrofolate reductase genes in Moldavian patients with ulcerative colitis: Genotype-phenotype correlation

BACKGROUND: Glutathione S-transferases (GSTM1, GSTT1, and GSTP1) and methylenetetrahydrofolate reductase (MTHFR) are important enzymes for protection against oxidative stress. In addition, MTHFR has an essential role in DNA synthesis, repair, and methylation. Their polymorphisms have been implicated...

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Detalles Bibliográficos
Autores principales: Varzari, Alexander, Deyneko, Igor V., Tudor, Elena, Turcan, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707243/
https://www.ncbi.nlm.nih.gov/pubmed/26862484
http://dx.doi.org/10.1016/j.mgene.2015.12.002