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The RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and Beyond
The small GTPase Ran regulates the interaction of transport receptors with a number of cellular cargo proteins. The high affinity binding of the GTP-bound form of Ran to import receptors promotes cargo release, whereas its binding to export receptors stabilizes their interaction with the cargo. This...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707252/ https://www.ncbi.nlm.nih.gov/pubmed/26793706 http://dx.doi.org/10.3389/fcell.2015.00082 |