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Transient Expression of Secretory IgA In Planta is Optimal Using a Multi-Gene Vector and may be Further Enhanced by Improving Joining Chain Incorporation

Secretory IgA (sIgA) is a crucial antibody in host defense at mucosal surfaces. It is a promising antibody isotype in a variety of therapeutic settings such as passive vaccination and treatment of inflammatory disorders. However, heterologous production of this heteromultimeric protein complex is st...

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Detalles Bibliográficos
Autores principales: Westerhof, Lotte B., Wilbers, Ruud H. P., van Raaij, Debbie R., van Wijk, Christina Z., Goverse, Aska, Bakker, Jaap, Schots, Arjen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707260/
https://www.ncbi.nlm.nih.gov/pubmed/26793201
http://dx.doi.org/10.3389/fpls.2015.01200