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Cognitive Training at a Young Age Attenuates Deficits in the zQ175 Mouse Model of HD

Huntington's Disease (HD) is a progressive neurodegenerative disorder that causes motor, cognitive, and psychiatric symptoms. In these experiments, we tested if operant training at an early age affected adult cognitive deficits in the zQ175 KI Het (zQ175) mouse model of HD. In Experiment 1 we t...

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Detalles Bibliográficos
Autores principales: Curtin, Paul C. P., Farrar, Andrew M., Oakeshott, Stephen, Sutphen, Jane, Berger, Jason, Mazzella, Matthew, Cox, Kimberly, He, Dansha, Alosio, William, Park, Larry C., Howland, David, Brunner, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707270/
https://www.ncbi.nlm.nih.gov/pubmed/26793080
http://dx.doi.org/10.3389/fnbeh.2015.00361