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A complex water network contributes to high-affinity binding in an antibody–antigen interface

This data article presents an analysis of structural water molecules in the high affinity interaction between a potent tumor growth inhibiting antibody (fragment), J22.9-xi, and the tumor marker antigen CD269 (B cell maturation antigen, BCMA). The 1.89 Å X-ray crystal structure shows exquisite detai...

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Detalles Bibliográficos
Autores principales: Marino, S.F., Olal, D., Daumke, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707293/
https://www.ncbi.nlm.nih.gov/pubmed/26862587
http://dx.doi.org/10.1016/j.dib.2015.12.023