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Antigen-Specific Regulatory T Cells and Low Dose of IL-2 in Treatment of Type 1 Diabetes

Regulatory T cells (Tregs) play an important role in preventing effector T-cell (Teff) targeting of self-antigens that can lead to tissue destruction in autoimmune settings, including type 1 diabetes (T1D). Autoimmunity is caused in part by an imbalance between Teff and Tregs. Early attempts to trea...

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Detalles Bibliográficos
Autores principales: Pham, Minh N., von Herrath, Matthias G., Vela, Jose Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707297/
https://www.ncbi.nlm.nih.gov/pubmed/26793191
http://dx.doi.org/10.3389/fimmu.2015.00651