Electroporated Antigen-Encoding mRNA Is Not a Danger Signal to Human Mature Monocyte-Derived Dendritic Cells

For therapeutic cancer vaccination, the adoptive transfer of mRNA-electroporated dendritic cells (DCs) is frequently performed, usually with monocyte-derived, cytokine-matured DCs (moDCs). However, DCs are rich in danger-sensing receptors which could recognize the exogenously delivered mRNA and indu...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoyer, Stefanie, Gerer, Kerstin F., Pfeiffer, Isabell A., Prommersberger, Sabrina, Höfflin, Sandra, Jaitly, Tanushree, Beltrame, Luca, Cavalieri, Duccio, Schuler, Gerold, Vera, Julio, Schaft, Niels, Dörrie, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707322/
https://www.ncbi.nlm.nih.gov/pubmed/26824052
http://dx.doi.org/10.1155/2015/952184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707322/
https://www.ncbi.nlm.nih.gov/pubmed/26824052
http://dx.doi.org/10.1155/2015/952184

Ejemplares similares