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Impact of Pancreatic Rat Islet Density on Cell Survival during Hypoxia

In bioartificial pancreases (BP), the number of islets needed to restore normoglycaemia in the diabetic patient is critical. However, the confinement of a high quantity of islets in a limited space may impact islet survival, particularly in regard to the low oxygen partial pressure (PO(2)) in such e...

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Detalles Bibliográficos
Autores principales: Rodriguez-Brotons, A., Bietiger, W., Peronet, C., Magisson, J., Sookhareea, C., Langlois, A., Mura, C., Jeandidier, N., Pinget, M., Sigrist, S., Maillard, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707363/
https://www.ncbi.nlm.nih.gov/pubmed/26824040
http://dx.doi.org/10.1155/2016/3615286