Endothelial Transdifferentiation of Tumor Cells Triggered by the Twist1-Jagged1-KLF4 Axis: Relationship between Cancer Stemness and Angiogenesis

Tumor hypoxia is associated with malignant biological phenotype including enhanced angiogenesis and metastasis. Hypoxia increases the expression of vascular endothelial cell growth factor (VEGF), which directly participates in angiogenesis by recruiting endothelial cells into hypoxic area and stimul...

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Detalles Bibliográficos
Autores principales: Chen, Hsiao-Fan, Wu, Kou-Juey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707371/
https://www.ncbi.nlm.nih.gov/pubmed/26823670
http://dx.doi.org/10.1155/2016/6439864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707371/
https://www.ncbi.nlm.nih.gov/pubmed/26823670
http://dx.doi.org/10.1155/2016/6439864

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