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Knock-down of ZBED6 in insulin-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro

The role of the novel transcription factor ZBED6 for the adhesion/clustering of insulin-producing mouse MIN6 and βTC6 cells was investigated. Zbed6-silencing in the insulin producing cells resulted in increased three-dimensional cell-cell clustering and decreased adhesion to mouse laminin and human...

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Detalles Bibliográficos
Autores principales: Wang, Xuan, Xie, Beichen, Qi, Yu, Wallerman, Ola, Vasylovska, Svitlana, Andersson, Leif, Kozlova, Elena Nickolaevna, Welsh, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707466/
https://www.ncbi.nlm.nih.gov/pubmed/26750727
http://dx.doi.org/10.1038/srep19006