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Evidence for redox sensing by a human cardiac calcium channel
Ion channels are critical to life and respond rapidly to stimuli to evoke physiological responses. Calcium influx into heart muscle occurs through the ion conducting α1C subunit (Ca(v)1.2) of the L-type Ca(2+) channel. Glutathionylation of Ca(v)1.2 results in increased calcium influx and is evident...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707475/ https://www.ncbi.nlm.nih.gov/pubmed/26750869 http://dx.doi.org/10.1038/srep19067 |