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Bright and photostable push-pull pyrene dye visualizes lipid order variation between plasma and intracellular membranes

Imaging lipid organization in cell membranes requires advanced fluorescent probes. Here, we show that a recently synthesized push-pull pyrene (PA), similarly to popular probe Laurdan, changes the emission maximum as a function of lipid order, but outperforms it by spectroscopic properties. In additi...

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Detalles Bibliográficos
Autores principales: Niko, Yosuke, Didier, Pascal, Mely, Yves, Konishi, Gen-ichi, Klymchenko, Andrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707542/
https://www.ncbi.nlm.nih.gov/pubmed/26750324
http://dx.doi.org/10.1038/srep18870