Preclinical toxicology of oncolytic adenovirus-mediated cytotoxic and interleukin-12 gene therapy for prostate cancer

The purpose of this study was to examine the toxicity of combining oncolytic adenovirus-mediated cytotoxic and interleukin 12 (IL-12) gene therapy in a preclinical model to support future phase 1 trials. One hundred and twenty C57BL/6 male mice received an intraprostatic injection of saline (n = 24)...

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Detalles Bibliográficos
Autores principales: Freytag, Svend O, Zhang, Yingshu, Siddiqui, Farzan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707660/
https://www.ncbi.nlm.nih.gov/pubmed/26767191
http://dx.doi.org/10.1038/mto.2015.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707660/
https://www.ncbi.nlm.nih.gov/pubmed/26767191
http://dx.doi.org/10.1038/mto.2015.6

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