Resveratrol ameliorates myocardial fibrosis by inhibiting ROS/ERK/TGF-β/periostin pathway in STZ-induced diabetic mice

BACKGROUND: Myocardial fibrosis is an essential hallmark of diabetic cardiomyopathy (DCM) contributing to cardiac dysfunctions. Resveratrol, an antioxidant, exerts its anti-fibrotic effect via inhibition of oxidative stress, while the underlying molecular mechanism remains largely elusive. Periostin...

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Detalles Bibliográficos
Autores principales: Wu, Han, Li, Guan-Nan, Xie, Jun, Li, Ran, Chen, Qin-Hua, Chen, Jian-Zhou, Wei, Zhong-Hai, Kang, Li-Na, Xu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707778/
https://www.ncbi.nlm.nih.gov/pubmed/26750922
http://dx.doi.org/10.1186/s12872-015-0169-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707778/
https://www.ncbi.nlm.nih.gov/pubmed/26750922
http://dx.doi.org/10.1186/s12872-015-0169-z

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