Induction of caspase-dependent extrinsic apoptosis by apigenin through inhibition of signal transducer and activator of transcription 3 (STAT3) signalling in HER2-overexpressing BT-474 breast cancer cells

Phytoestrogen intake is known to be beneficial to decrease breast cancer incidence and progression. But its molecular mechanisms of action are still unknown. The present study aimed to examine the effect of apigenin on proliferation and apoptosis in HER2-expressing breast cancer cells. In our experi...

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Detalles Bibliográficos
Autores principales: Seo, Hye-Sook, Jo, Jae Kyung, Ku, Jin Mo, Choi, Han-Seok, Choi, Youn Kyung, Woo, Jong-Kyu, in Kim, Hyo, Kang, Soo-yeon, Lee, Kang min, Nam, Koong Won, Park, Namkyu, Jang, Bo-Hyoung, Shin, Yong Cheol, Ko, Seong-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708008/
https://www.ncbi.nlm.nih.gov/pubmed/26500281
http://dx.doi.org/10.1042/BSR20150165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708008/
https://www.ncbi.nlm.nih.gov/pubmed/26500281
http://dx.doi.org/10.1042/BSR20150165

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