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Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites

This work reports the in vitro activity against Plasmodium falciparumblood forms (W2 clone, chloroquine-resistant) of tamoxifen-based compounds and their ferrocenyl (ferrocifens) and ruthenocenyl (ruthenocifens) derivatives, as well as their cytotoxicity against HepG2 human hepatoma cells. Surprisin...

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Detalles Bibliográficos
Autores principales: de Souza, Nicolli Bellotti, Aguiar, Anna Caroline Campos, de Oliveira, Alane Cabral, Top, Siden, Pigeon, Pascal, Jaouen, Gérard, Goulart, Marilia Oliveira Fonseca, Krettli, Antoniana Ursine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708017/
https://www.ncbi.nlm.nih.gov/pubmed/26602875
http://dx.doi.org/10.1590/0074-02760150163