Cargando…

Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites

This work reports the in vitro activity against Plasmodium falciparumblood forms (W2 clone, chloroquine-resistant) of tamoxifen-based compounds and their ferrocenyl (ferrocifens) and ruthenocenyl (ruthenocifens) derivatives, as well as their cytotoxicity against HepG2 human hepatoma cells. Surprisin...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Souza, Nicolli Bellotti, Aguiar, Anna Caroline Campos, de Oliveira, Alane Cabral, Top, Siden, Pigeon, Pascal, Jaouen, Gérard, Goulart, Marilia Oliveira Fonseca, Krettli, Antoniana Ursine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Instituto Oswaldo Cruz, Ministério da Saúde 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708017/ https://www.ncbi.nlm.nih.gov/pubmed/26602875 http://dx.doi.org/10.1590/0074-02760150163

Ejemplares similares

Commercial drugs containing flavonoids are active in mice with malaria and in vitro against chloroquine-resistant Plasmodium falciparum
por: Penna-Coutinho, Julia, et al.
Publicado: (2018)

Antiplasmodial activity of chloroquine analogs against chloroquine-resistant parasites, docking studies and mechanisms of drug action
por: de Souza, Nicolli B, et al.
Publicado: (2014)

Blood shizonticidal activities of phenazines and naphthoquinoidal compounds against Plasmodium falciparum in vitro and in mice malaria studies
por: de Souza, Nicolli Bellotti, et al.
Publicado: (2014)

Aspidosperma (Apocynaceae) plant cytotoxicity and activity towards malaria parasites. Part II: experimental studies with Aspidosperma ramiflorum in vivo and in vitro
por: Aguiar, Anna CC, et al.
Publicado: (2015)

Organometallic cis-Dichlorido Ruthenium(II) Ammine Complexes
por: Betanzos-Lara, Soledad, et al.
Publicado: (2011)

Anticancer evaluation of new organometallic ruthenium(ii) flavone complexes
por: Khater, Mai, et al.
Publicado: (2022)

Antimalarial Activity of Potential Inhibitors of Plasmodium falciparum Lactate Dehydrogenase Enzyme Selected by Docking Studies
por: Penna-Coutinho, Julia, et al.
Publicado: (2011)

Antiplasmodial, Trypanocidal, and Genotoxicity In Vitro Assessment of New Hybrid α,α-Difluorophenylacetamide-statin Derivatives
por: Araujo-Lima, Carlos Fernando, et al.
Publicado: (2023)

Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes
por: Hanif, Muhammad, et al.
Publicado: (2013)

The Application of Reversible Intramolecular Sulfonamide Ligation to Modulate Reactivity in Organometallic Ruthenium(II) Diamine Complexes
por: Kemp, Samuel A., et al.
Publicado: (2020)

Reactivity of non-organometallic ruthenium(II) polypyridyl complexes and their application as catalysts for hydride transfer reactions
por: Chrzanowska, Marta, et al.
Publicado: (2023)

New linear antiplasmodial peptides related to angiotensin II
por: Silva, Adriana Farias, et al.
Publicado: (2015)

Effect of the amino chain length and the transformation into citric acid salts of aryl-diphenyl-butenes and ferrocenyl-diphenyl-butenes bearing two dimethylaminoalkyl chains on their antimicrobial activities
por: Jellali, Karim, et al.
Publicado: (2013)

Aspidosperma pyrifolium, a medicinal plant from the Brazilian caatinga, displays a high antiplasmodial activity and low cytotoxicity
por: Ceravolo, Isabela P., et al.
Publicado: (2018)

A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties
por: Wang, Yong, et al.
Publicado: (2017)

Atypical McMurry Cross-Coupling Reactions Leading to a New Series of Potent Antiproliferative Compounds Bearing the Key [Ferrocenyl-Ene-Phenol] Motif
por: Pigeon, Pascal, et al.
Publicado: (2014)

In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer
por: Aird, R E, et al.
Publicado: (2002)

Cell Death Mechanism of Organometallic Ruthenium(II) and Iridium(III) Arene Complexes on HepG2 and Vero Cells
por: Kavukcu, Serdar Batıkan, et al.
Publicado: (2023)

Angiotensin II-derived constrained peptides with antiplasmodial activity and suppressed vasoconstriction
por: Silva, Adriana Farias, et al.
Publicado: (2017)

A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies
por: Hsia, Chih-Hsuan, et al.
Publicado: (2017)

Electronic effects on the mechanism of the NAD(+) coenzyme reduction catalysed by a non-organometallic ruthenium(ii) polypyridyl amine complex in the presence of formate
por: Chrzanowska, Marta, et al.
Publicado: (2022)

Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti-malarials and gene characterization in Rondônia, West Amazon, Brazil
por: Aguiar, Anna Caroline C, et al.
Publicado: (2014)

Surface-Bound Ruthenium Diimine Organometallic Complexes: Excited-State Properties
por: Abbott, Geoffrey, et al.
Publicado: (2014)

Photocytotoxic Activity of Ruthenium(II) Complexes with Phenanthroline-Hydrazone Ligands
por: Silva-Caldeira, Priscila Pereira, et al.
Publicado: (2021)

Antimalarial Activity and Mechanisms of Action of Two Novel 4-Aminoquinolines against Chloroquine-Resistant Parasites
por: Aguiar, Anna Caroline Campos, et al.
Publicado: (2012)

Aspidosperma (Apocynaceae) plant cytotoxicity and activity towards malaria parasites. Part I: Aspidosperma nitidum (Benth) used as a remedy to treat fever and malaria in the Amazon
por: Coutinho, Julia Penna, et al.
Publicado: (2013)

Photorelease of Pyridyl Esters in Organometallic Ru(II) Arene Complexes
por: Habtemariam, Abraha, et al.
Publicado: (2015)

Binding of Organometallic Ruthenium Anticancer Complexes to DNA: Thermodynamic Base and Sequence Selectivity
por: Liu, Suyan, et al.
Publicado: (2018)

Author Correction: A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies
por: Hsia, Chih-Hsuan, et al.
Publicado: (2020)

MEFAS, a hybrid of artesunate-mefloquine active against asexual stages of Plasmodium vivax in field isolates, inhibits malaria transmission
por: Penna-Coutinho, Julia, et al.
Publicado: (2021)

N-Acetylcysteine (NAC): Impacts on Human Health
por: Tenório, Micaely Cristina dos Santos, et al.
Publicado: (2021)

Studies on Activities and Chemical Characterization of Medicinal Plants in Search for New Antimalarials: A Ten Year Review on Ethnopharmacology
por: Ceravolo, Isabela P., et al.
Publicado: (2021)

Cross-Talk between Oxidative Stress and Inflammation in Preeclampsia
por: Tenório, Marilene Brandão, et al.
Publicado: (2019)

Mesoporous silica nanocarriers encapsulated antimalarials with high therapeutic performance
por: Amolegbe, Saliu Alao, et al.
Publicado: (2018)

Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum
por: Chierrito, Talita PC, et al.
Publicado: (2014)

Selection of a Suitable Disc Bioassay for the Screening of Anti-Tumor Molecules
por: Trigui, Fatma, et al.
Publicado: (2013)

New Organometallic Ru(II) Compounds with Lonidamine Motif as Antitumor Agents
por: Shutkov, Ilya A., et al.
Publicado: (2023)

New Heteroleptic Ruthenium(II) Complexes with Sulfamethoxypyridazine and Diimines as Potential Antitumor Agents
por: de Melo, Ariane C.C., et al.
Publicado: (2019)

Gestational Diabetes Mellitus: The Crosslink among Inflammation, Nitroxidative Stress, Intestinal Microbiota and Alternative Therapies
por: de Mendonça, Elaine Luiza Santos Soares, et al.
Publicado: (2022)

Nanostructured Lipid Systems as a Strategy to Improve the in Vitro Cytotoxicity of Ruthenium(II) Compounds
por: de Freitas, Eduardo Sinesio, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_guhk1d8ku8j68nh3bbhh7i8k3e