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Co-administration of plasmid-encoded granulocyte-macrophage colony-stimulating factor increases human immunodeficiency virus-1 DNA vaccine-induced polyfunctional CD4(+) T-cell responses

T-cell based vaccines against human immunodeficiency virus (HIV) generate specific responses that may limit both transmission and disease progression by controlling viral load. Broad, polyfunctional, and cytotoxic CD4(+)T-cell responses have been associated with control of simian immunodeficiency vi...

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Detalles Bibliográficos
Autores principales: Santana, Vinicius Canato, Almeida, Rafael Ribeiro, Ribeiro, Susan Pereira, Ferreira, Luís Carlos de Souza, Kalil, Jorge, Rosa, Daniela Santoro, Cunha-Neto, Edecio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708021/
https://www.ncbi.nlm.nih.gov/pubmed/26602876
http://dx.doi.org/10.1590/0074-02760150283