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Evaluating the use of HILIC in large-scale, multi dimensional proteomics: Horses for courses?
Despite many recent advances in instrumentation, the sheer complexity of biological samples remains a major challenge in large-scale proteomics experiments, reflecting both the large number of protein isoforms and the wide dynamic range of their expression levels. However, while the dynamic range of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708065/ https://www.ncbi.nlm.nih.gov/pubmed/26869852 http://dx.doi.org/10.1016/j.ijms.2015.07.029 |