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The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators

Insulin/IGF-1 signaling (IIS) is a critical regulator of an organism’s most important biological decisions, from growth, development, and metabolism to reproduction and longevity. It primarily does so through the activity of the DAF-16/FOXO transcription factor, whose global targets were identified...

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Detalles Bibliográficos
Autores principales: Kaletsky, Rachel, Lakhina, Vanisha, Arey, Rachel, Williams, April, Landis, Jessica, Ashraf, Jasmine, Murphy, Coleen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708089/
https://www.ncbi.nlm.nih.gov/pubmed/26675724
http://dx.doi.org/10.1038/nature16483