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The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators
Insulin/IGF-1 signaling (IIS) is a critical regulator of an organism’s most important biological decisions, from growth, development, and metabolism to reproduction and longevity. It primarily does so through the activity of the DAF-16/FOXO transcription factor, whose global targets were identified...
Autores principales: | Kaletsky, Rachel, Lakhina, Vanisha, Arey, Rachel, Williams, April, Landis, Jessica, Ashraf, Jasmine, Murphy, Coleen T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708089/ https://www.ncbi.nlm.nih.gov/pubmed/26675724 http://dx.doi.org/10.1038/nature16483 |
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