Design and evaluation of novel interferon lambda analogs with enhanced antiviral activity and improved drug attributes

Type III interferons (IFNs) (also called IFN-λ: IFN-λ1, IFN-λ2, IFN-λ3, and IFN-λ4) are critical players in the defense against viral infection of mucosal epithelial cells, where the activity of type I IFNs is weak, and unlike type I IFNs that are associated with severe and diverse side effects, typ...

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Detalles Bibliográficos
Autores principales: Yu, Debin, Zhao, Mingzhi, Dong, Liwei, Zhao, Lu, Zou, Mingwei, Sun, Hetong, Zhang, Mengying, Liu, Hongyu, Zou, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708225/
https://www.ncbi.nlm.nih.gov/pubmed/26792983
http://dx.doi.org/10.2147/DDDT.S91455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708225/
https://www.ncbi.nlm.nih.gov/pubmed/26792983
http://dx.doi.org/10.2147/DDDT.S91455

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