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AB188. Meiotic prophase I defects in an oligospermic man with Wolf-Hirschhorn syndrome with ring chromosome 4

BACKGROUND: Ring chromosomes are often associated with spermatogenetic failure. However, the mechanism is poorly understood. We here reported a single man with severe oligospermia and a ring chromosome 4 with a microdeletion at 4p16.3. METHODS: Synapsis (asSCP3), recombination (as MLH1) and transcri...

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Detalles Bibliográficos
Autores principales: Yao, Qi, Wang, Liu, Yao, Bing, Gao, Hongliu, Li, Weiwei, Xia, Xinyi, Shi, Qinghua, Cui, Yingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708340/
http://dx.doi.org/10.3978/j.issn.2223-4683.2014.s188