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AB111. Synthesizing an AND gate genetic circuit for identification of bladder cancer cells based on CRISPR-Cas9

BACKGROUND: Because of the lack of an ideal promoter that selectively identifies cancer cells and robustly drives therapeutic gene expression, the conventional strategy for cancer gene therapy offers limited control of specificity and efficacy. A possible way to overcome these limitations is to cons...

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Detalles Bibliográficos
Autores principales: Liu, Yuchen, Huang, Weiren, Cai, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708460/
http://dx.doi.org/10.3978/j.issn.2223-4683.2014.s111