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AB130. ASC-J9 suppresses renal cell carcinoma progression by targeting an androgen receptor-dependent HIF2α/VEGF signaling pathway

Males have a higher incidence of renal cell carcinoma (RCC) than females, but the reason for this gender difference is unknown. Addressing this question, we report the discovery of an androgen receptor (AR)-induced HIF2α/VEGF signal that drives RCC progression. AR attenuation or augmentation in RCC...

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Detalles Bibliográficos
Autores principales: He, Dalin, Li, Lei, Zhu, Gguodong, Liang, Liang, Guan, Zhenfeng, Chang, Luke, Chen, Yuan, Yeh, Shuyuan, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708530/
http://dx.doi.org/10.3978/j.issn.2223-4683.2014.s130