Cargando…

AB130. ASC-J9 suppresses renal cell carcinoma progression by targeting an androgen receptor-dependent HIF2α/VEGF signaling pathway

Males have a higher incidence of renal cell carcinoma (RCC) than females, but the reason for this gender difference is unknown. Addressing this question, we report the discovery of an androgen receptor (AR)-induced HIF2α/VEGF signal that drives RCC progression. AR attenuation or augmentation in RCC...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Dalin, Li, Lei, Zhu, Gguodong, Liang, Liang, Guan, Zhenfeng, Chang, Luke, Chen, Yuan, Yeh, Shuyuan, Chang, Chawnshang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2014
Materias:	Abstract Publication Urology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708530/ http://dx.doi.org/10.3978/j.issn.2223-4683.2014.s130

Ejemplares similares

ASC-J9® increases the bladder cancer chemotherapy efficacy via altering the androgen receptor (AR) and NF-κB survival signals
por: Huang, Chi-Ping, et al.
Publicado: (2019)

Targeting inflammatory cytokines-androgen receptor (AR) signaling with ASC-J9(®) to better battle prostate cancer progression
por: Izumi, Kouji, et al.
Publicado: (2013)

New therapy with ASC-J9(®) to suppress the prostatitis via altering the cytokine CCL2 signals
por: Lin, Shin-Jen, et al.
Publicado: (2016)

ASC-J9® suppresses prostate cancer cell proliferation and invasion via altering the ATF3-PTK2 signaling
por: Tian, Hao, et al.
Publicado: (2021)

Androgen Receptor Enhances Kidney Stone-CaOx Crystal Formation via Modulation of Oxalate Biosynthesis & Oxidative Stress
por: Liang, Liang, et al.
Publicado: (2014)

Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population
por: Li, Lei, et al.
Publicado: (2015)

Correction: Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population
por: Li, Lei, et al.
Publicado: (2016)

Androgen receptor (AR) pathophysiological roles in androgen-related diseases in skin, bone/muscle, metabolic syndrome and neuron/immune systems: lessons learned from mice lacking AR in specific cells
por: Chang, Chawnshang, et al.
Publicado: (2013)

Androgen Receptor Roles in Insulin Resistance and Obesity in Males: The Linkage of Androgen-Deprivation Therapy to Metabolic Syndrome
por: Yu, I-Chen, et al.
Publicado: (2014)

Effectiveness of cognitive behavioural therapy on quality of life in patients with prostate cancer after androgen deprivation therapy: a protocol for systematic review and meta-analysis
por: Yuan, Fan, et al.
Publicado: (2021)

Association between ischaemic bowel syndromes and androgen deprivation therapy in patients with prostate cancer: a retrospective cohort study
por: Chiang, I-Ni, et al.
Publicado: (2017)

AB131. Novel green-light KTP laser en bloc enucleation for nonmuscle-invasive bladder cancer: technique and initial clinical experience
por: He, Dalin, et al.
Publicado: (2014)

Persistent Testosterone Suppression After Cessation of Androgen Deprivation Therapy for Prostate Cancer
por: Delgado, Jessica, et al.
Publicado: (2022)

Factors Associated With Restarting Androgenic Anabolic Steroids After Cessation in Men With Infertility: A Retrospective Analysis
por: White, Josh, et al.
Publicado: (2023)

Infiltrating neutrophils increase bladder cancer cell invasion via modulation of androgen receptor (AR)/MMP13 signals
por: Lin, ChangYi, et al.
Publicado: (2015)

Sorafenib with ASC‐J9(®) synergistically suppresses the HCC progression via altering the pSTAT3‐CCL2/Bcl2 signals
por: Xu, Junjie, et al.
Publicado: (2016)

Development of UK guidance on the management of erectile dysfunction resulting from radical radiotherapy and androgen deprivation therapy for prostate cancer
por: White, I D, et al.
Publicado: (2015)

Decision analytic cost-effectiveness model to compare prostate cryotherapy to androgen deprivation therapy for treatment of radiation recurrent prostate cancer
por: Boyd, Kathleen A, et al.
Publicado: (2015)

Androgen deprivation therapy and the risk of iron-deficiency anaemia among patients with prostate cancer: a population-based cohort study
por: Wu, Fang-Jen, et al.
Publicado: (2020)

Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokines
por: Lai, Kuo-Pao, et al.
Publicado: (2012)

Gonadotropin-releasing hormone antagonists versus standard androgen suppression therapy for advanced prostate cancer A systematic review with meta-analysis
por: Kunath, Frank, et al.
Publicado: (2015)

Infiltrated pre-adipocytes increase prostate cancer metastasis via modulation of the miR-301a/androgen receptor (AR)/TGF-β1/Smad/MMP9 signals
por: Xie, Hongjun, et al.
Publicado: (2015)

Group-based exercise in daily clinical practice to improve physical fitness in men with prostate cancer undergoing androgen deprivation therapy: study protocol
por: Østergren, Peter, et al.
Publicado: (2016)

Correction: Infiltrated pre-adipocytes increase prostate cancer metastasis via modulation of the miR-301a/androgen receptor (AR)/TGF-β1/Smad/MMP9 signals
por: Xie, Hongjun, et al.
Publicado: (2016)

AB130. The expression and clinical significance of HIF-1α in bladder urothelial carcinoma
por: Fan, Haitao
Publicado: (2016)

Stereotactic body radiotherapy (SBRT) versus androgen deprivation therapy (ADT) for oligometastatic prostate cancer: protocol for a prospective randomised control clinical trial
por: Zhao, Xianzhi, et al.
Publicado: (2022)

Randomised double-blind phase 3 clinical study testing impact of atorvastatin on prostate cancer progression after initiation of androgen deprivation therapy: study protocol
por: Siltari, Aino, et al.
Publicado: (2022)

Utility of Post-ureteroscopy Lesion Scale (PULS) in Per-operative Decision-Making for the Need of Double J Stent
por: Pervaiz, Arsalan, et al.
Publicado: (2022)

Comparative Study of Externalized Ureteral Catheter Versus Double-J Stent on Percutaneous Nephrolithotomy: A Randomized Controlled Trial
por: Habib, Bilal, et al.
Publicado: (2022)

Early Versus Delayed Double J Stent Removal in Deceased Donor Renal Transplant Recipients: A Prospective Comparative Study
por: Appiya Ramamoorthy, Balaji, et al.
Publicado: (2018)

Association Between Ureteral Double J Stent Colonization and Lower Urinary Tract Symptom Severity: A Cross-Sectional Study
por: Hussain, Malik Hatim, et al.
Publicado: (2021)

ASC modulates HIF-1α stability and induces cell mobility in OSCC
por: Wu, Chi-Sheng, et al.
Publicado: (2020)

Long-term urinary tract effect of ileal conduit after radical cystectomy compared with bladder preservation: a nationwide, population-based cohort study with propensity score-matching analysis
por: Liu, Yu Liang, et al.
Publicado: (2018)

Androgen deprivation therapy for prostate cancer and risk of dementia
por: Robinson, David, et al.
Publicado: (2019)

Tumor microenvironment B cells increase bladder cancer metastasis via modulation of the IL-8/androgen receptor (AR)/MMPs signals
por: Ou, Zhenyu, et al.
Publicado: (2015)

Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling
por: Lin, T-H, et al.
Publicado: (2013)

Relationship among diet habit and lower urinary tract symptoms and sexual function in outpatient-based males with LUTS/BPH: a multiregional and cross-sectional study in China
por: Chen, Yuke, et al.
Publicado: (2016)

Infiltrating neutrophils promote renal cell carcinoma progression via VEGFa/HIF2α and estrogen receptor β signals
por: Song, Wenbin, et al.
Publicado: (2015)

Abnormal Mitochondrial Function and Impaired Granulosa Cell Differentiation in Androgen Receptor Knockout Mice
por: Wang, Ruey-Sheng, et al.
Publicado: (2015)

Aggressive Bladder Tumour Following Clam Ileocystoplasty: A Rare Long-Term Complication
por: Ononye, Reginald, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_joajmo3grbk07klqihniv737be