AB198. Estrogen attenuates the TGFβ1-induced conversion of primary penile tunica albuginea fibroblasts into myofibroblasts and inhibits collagen production and myofibroblast contraction by modulating the Smad and Rho/ROCK signaling pathways

OBJECTIVE: The transformation of penile tunica albuginea fibroblasts (TAFs) into myofibroblasts plays an important role in the pathological progress of Peyronie’s disease (PD). However, no treatment is currently available to address this issue. Estrogen has been shown to inhibit the progression of f...

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Detalles Bibliográficos
Autores principales: Jiang, Hesong, Dai, Yutian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2015
Materias:
Accepted Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708689/
http://dx.doi.org/10.3978/j.issn.2223-4683.2015.s198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708689/
http://dx.doi.org/10.3978/j.issn.2223-4683.2015.s198

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