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AB198. Estrogen attenuates the TGFβ1-induced conversion of primary penile tunica albuginea fibroblasts into myofibroblasts and inhibits collagen production and myofibroblast contraction by modulating the Smad and Rho/ROCK signaling pathways
OBJECTIVE: The transformation of penile tunica albuginea fibroblasts (TAFs) into myofibroblasts plays an important role in the pathological progress of Peyronie’s disease (PD). However, no treatment is currently available to address this issue. Estrogen has been shown to inhibit the progression of f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AME Publishing Company
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708689/ http://dx.doi.org/10.3978/j.issn.2223-4683.2015.s198 |