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AB174. VHL protein: a new therapeutic target of renal cell carcinoma

OBJECTIVE: Although VHL gene is well-known as the most important tumor suppressor gene in renal cell carcinoma (RCC), the exact mechanism of VHL gene missense mutation in the pathogenesis of RCC is unclear. We studied on the mechanism of VHL gene missense mutation in the function loss of VHL protein...

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Detalles Bibliográficos
Autores principales: Wang, Jiangyi, Li, Teng, Ning, Xianghui, Peng, Shuanghe, Chen, Jinchao, Gong, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708851/
http://dx.doi.org/10.3978/j.issn.2223-4683.2015.s174