Irradiation-injured brain tissues can self-renew in the absence of the pivotal tumor suppressor p53 in the medaka ( Oryzias latipes ) embryo

The tumor suppressor protein, p53, plays pivotal roles in regulating apoptosis and proliferation in the embryonic and adult central nervous system (CNS) following neuronal injuries such as those induced by ionizing radiation. There is increasing evidence that p53 negatively regulates the self-renewa...

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Detalles Bibliográficos
Autores principales: Yasuda, Takako, Kimori, Yoshitaka, Nagata, Kento, Igarashi, Kento, Watanabe-Asaka, Tomomi, Oda, Shoji, Mitani, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708913/
https://www.ncbi.nlm.nih.gov/pubmed/26410759
http://dx.doi.org/10.1093/jrr/rrv054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708913/
https://www.ncbi.nlm.nih.gov/pubmed/26410759
http://dx.doi.org/10.1093/jrr/rrv054

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