Design, synthesis, and antihypertensive activity of curcumin-inspired compounds via ACE inhibition and vasodilation, along with a bioavailability study for possible benefit in cardiovascular diseases

This study describes the synthesis of a novel series of curcumin-inspired compounds via a facile synthetic route. The structures of these derivatives were ascertained using various spectroscopic and analytic techniques. The pharmacological effects of the target analogs were assessed by assaying thei...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuang, Xiao-dong, Liao, Li-zhen, Dong, Xiao-bian, Hu, Xun, Guo, Yue, Du, Zhi-min, Liao, Xin-xue, Wang, Li-chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708961/
https://www.ncbi.nlm.nih.gov/pubmed/26792980
http://dx.doi.org/10.2147/DDDT.S96315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708961/
https://www.ncbi.nlm.nih.gov/pubmed/26792980
http://dx.doi.org/10.2147/DDDT.S96315

Ejemplares similares