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Curcumin Suppresses Proliferation and Migration of MDA-MB-231 Breast Cancer Cells through Autophagy-Dependent Akt Degradation

Previous studies have evidenced that the anticancer potential of curcumin (diferuloylmethane), a main yellow bioactive compound from plant turmeric was mediated by interfering with PI3K/Akt signaling. However, the underlying molecular mechanism is still poorly understood. This study experimentally r...

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Detalles Bibliográficos
Autores principales: Guan, Feng, Ding, Youming, Zhang, Yemin, Zhou, Yu, Li, Mingxin, Wang, Changhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708990/
https://www.ncbi.nlm.nih.gov/pubmed/26752181
http://dx.doi.org/10.1371/journal.pone.0146553