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Abnormal Skeletal Muscle Regeneration plus Mild Alterations in Mature Fiber Type Specification in Fktn-Deficient Dystroglycanopathy Muscular Dystrophy Mice

Glycosylated α-dystroglycan provides an essential link between extracellular matrix proteins, like laminin, and the cellular cytoskeleton via the dystrophin-glycoprotein complex. In secondary dystroglycanopathy muscular dystrophy, glycosylation abnormalities disrupt a complex O-mannose glycan necess...

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Detalles Bibliográficos
Autores principales: Foltz, Steven J., Modi, Jill N., Melick, Garrett A., Abousaud, Marin I., Luan, Junna, Fortunato, Marisa J., Beedle, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708996/
https://www.ncbi.nlm.nih.gov/pubmed/26751696
http://dx.doi.org/10.1371/journal.pone.0147049