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Replication of the Shrimp Virus WSSV Depends on Glutamate-Driven Anaplerosis

Infection with the white spot syndrome virus (WSSV) induces a metabolic shift in shrimp that resembles the “Warburg effect” in mammalian cells. This effect is triggered via activation of the PI3K-Akt-mTOR pathway, and it is usually accompanied by the activation of other metabolic pathways that provi...

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Detalles Bibliográficos
Autores principales: Li, Chun-Yuan, Wang, Yi-Jan, Huang, Shiao-Wei, Cheng, Cheng-Shun, Wang, Han-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709008/
https://www.ncbi.nlm.nih.gov/pubmed/26751681
http://dx.doi.org/10.1371/journal.pone.0146902