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A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis

We tested for germline variants showing association to colon cancer metastasis using a genome-wide association study that compared Ashkenazi Jewish individuals with stage IV metastatic colon cancers versus those with stage I or II non-metastatic colon cancers. In a two-stage study design, we demonst...

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Detalles Bibliográficos
Autores principales: Markowitz, Sanford D., Nock, Nora L., Schmit, Stephanie L., Stadler, Zsofia K., Joseph, Vijai, Zhang, Lu, Willis, Joseph E., Scacheri, Peter, Veigl, Martina, Adams, Mark D., Raskin, Leon, Sullivan, John F., Stratton, Kelly, Shia, Jinru, Ellis, Nathan, Rennert, Hedy S., Manschreck, Christopher, Li, Li, Offit, Kenneth, Elston, Robert C., Rennert, Gadi, Gruber, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709047/
https://www.ncbi.nlm.nih.gov/pubmed/26751797
http://dx.doi.org/10.1371/journal.pone.0146435