Cargando…

Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines

MTAP is a ubiquitously expressed gene important for adenine and methionine salvage. The gene is located at 9p21, a chromosome region often deleted in breast carcinomas, similar to CDKN2A, a recognized tumor suppressor gene. Several research groups have shown that MTAP acts as a tumor suppressor, and...

Descripción completa

Detalles Bibliográficos
Autores principales: de Oliveira, Sarah Franco Vieira, Ganzinelli, Monica, Chilà, Rosaria, Serino, Leandro, Maciel, Marcos Euzébio, Urban, Cícero de Andrade, de Lima, Rubens Silveira, Cavalli, Iglenir João, Generali, Daniele, Broggini, Massimo, Damia, Giovanna, Ribeiro, Enilze Maria de Souza Fonseca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709099/
https://www.ncbi.nlm.nih.gov/pubmed/26751376
http://dx.doi.org/10.1371/journal.pone.0145647