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A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus

To date there are no approved antiviral drugs for the treatment of Ebola virus disease (EVD). While a number of candidate drugs have shown limited efficacy in vitro and/or in non-human primate studies, differences in experimental methodologies make it difficult to compare their therapeutic effective...

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Detalles Bibliográficos
Autores principales: McCarthy, Stephen D. S., Majchrzak-Kita, Beata, Racine, Trina, Kozlowski, Hannah N., Baker, Darren P., Hoenen, Thomas, Kobinger, Gary P., Fish, Eleanor N., Branch, Donald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709101/
https://www.ncbi.nlm.nih.gov/pubmed/26752302
http://dx.doi.org/10.1371/journal.pntd.0004364