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A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus
To date there are no approved antiviral drugs for the treatment of Ebola virus disease (EVD). While a number of candidate drugs have shown limited efficacy in vitro and/or in non-human primate studies, differences in experimental methodologies make it difficult to compare their therapeutic effective...
Autores principales: | McCarthy, Stephen D. S., Majchrzak-Kita, Beata, Racine, Trina, Kozlowski, Hannah N., Baker, Darren P., Hoenen, Thomas, Kobinger, Gary P., Fish, Eleanor N., Branch, Donald R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709101/ https://www.ncbi.nlm.nih.gov/pubmed/26752302 http://dx.doi.org/10.1371/journal.pntd.0004364 |
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