Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1

Replication forks are vulnerable to wayward nuclease activities. We report here our discovery of a new member in guarding genome stability at replication forks. We previously isolated a Drosophila mutation, wuho (wh, no progeny), characterized by a severe fertility defect and affecting expression of...

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Detalles Bibliográficos
Autores principales: Cheng, I-Cheng, Chen, Betty Chamay, Shuai, Hung-Hsun, Chien, Fan-Ching, Chen, Peilin, Hsieh, Tao-shih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709127/
https://www.ncbi.nlm.nih.gov/pubmed/26751069
http://dx.doi.org/10.1371/journal.pbio.1002349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709127/
https://www.ncbi.nlm.nih.gov/pubmed/26751069
http://dx.doi.org/10.1371/journal.pbio.1002349

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