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Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1
Replication forks are vulnerable to wayward nuclease activities. We report here our discovery of a new member in guarding genome stability at replication forks. We previously isolated a Drosophila mutation, wuho (wh, no progeny), characterized by a severe fertility defect and affecting expression of...
Autores principales: | Cheng, I-Cheng, Chen, Betty Chamay, Shuai, Hung-Hsun, Chien, Fan-Ching, Chen, Peilin, Hsieh, Tao-shih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709127/ https://www.ncbi.nlm.nih.gov/pubmed/26751069 http://dx.doi.org/10.1371/journal.pbio.1002349 |
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