Rapamycin Inhibits Oxidized Low Density Lipoprotein Uptake in Human Umbilical Vein Endothelial Cells via mTOR/NF-κB/LOX-1 Pathway

BACKGROUND: Lectin-like oxidized low-density lipoprotein-1 (LOX-1) is the major receptor for oxidized low density lipoprotein (ox-LDL) uptake in human umbilical vein endothelial cells (HUVECs). Previously, we found that rapamycin inhibited ox-LDL accumulation in HUVECs, and this effect was related t...

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Detalles Bibliográficos
Autores principales: Zhou, Yan-De, Cao, Xue-Qin, Liu, Zhi-Hua, Cao, Yong-Jun, Liu, Chun-Feng, Zhang, Yan-Lin, Xie, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709184/
https://www.ncbi.nlm.nih.gov/pubmed/26752047
http://dx.doi.org/10.1371/journal.pone.0146777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709184/
https://www.ncbi.nlm.nih.gov/pubmed/26752047
http://dx.doi.org/10.1371/journal.pone.0146777

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