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Trade-Offs of Escherichia coli Adaptation to an Intracellular Lifestyle in Macrophages
The bacterium Escherichia coli exhibits remarkable genomic and phenotypic variation, with some pathogenic strains having evolved to survive and even replicate in the harsh intra-macrophage environment. The rate and effects of mutations that can cause pathoadaptation are key determinants of the pace...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709186/ https://www.ncbi.nlm.nih.gov/pubmed/26752723 http://dx.doi.org/10.1371/journal.pone.0146123 |