Engineering Yarrowia lipolytica for Campesterol Overproduction

Campesterol is an important precursor for many sterol drugs, e.g. progesterone and hydrocortisone. In order to produce campesterol in Yarrowia lipolytica, C-22 desaturase encoding gene ERG5 was disrupted and the heterologous 7-dehydrocholesterol reductase (DHCR7) encoding gene was constitutively exp...

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Detalles Bibliográficos
Autores principales: Du, Hao-Xing, Xiao, Wen-Hai, Wang, Ying, Zhou, Xiao, Zhang, Yu, Liu, Duo, Yuan, Ying-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709189/
https://www.ncbi.nlm.nih.gov/pubmed/26751680
http://dx.doi.org/10.1371/journal.pone.0146773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709189/
https://www.ncbi.nlm.nih.gov/pubmed/26751680
http://dx.doi.org/10.1371/journal.pone.0146773

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