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The Molecular Basis of Polyunsaturated Fatty Acid Interactions with the Shaker Voltage-Gated Potassium Channel

Voltage-gated potassium (K(V)) channels are membrane proteins that respond to changes in membrane potential by enabling K(+) ion flux across the membrane. Polyunsaturated fatty acids (PUFAs) induce channel opening by modulating the voltage-sensitivity, which can provide effective treatment against r...

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Detalles Bibliográficos
Autores principales: Yazdi, Samira, Stein, Matthias, Elinder, Fredrik, Andersson, Magnus, Lindahl, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709198/
https://www.ncbi.nlm.nih.gov/pubmed/26751683
http://dx.doi.org/10.1371/journal.pcbi.1004704