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Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy
Balance between cell growth and proliferation determines cell size homeostasis, but little is known about how metabolic pathways are involved in the maintenance of this balance. Here, we perform a screen with a library of clinically used drug molecules for their effects on cell size. We find that st...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cell Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709259/ https://www.ncbi.nlm.nih.gov/pubmed/26686643 http://dx.doi.org/10.1016/j.celrep.2015.11.045 |