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The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering

Cohesin tethers together regions of DNA, thereby mediating higher order chromatin organization that is critical for sister chromatid cohesion, DNA repair and transcriptional regulation. Cohesin contains a heterodimeric ATP-binding Cassette (ABC) ATPase comprised of Smc1 and Smc3 ATPase active sites....

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Detalles Bibliográficos
Autores principales: Çamdere, Gamze, Guacci, Vincent, Stricklin, Jeremiah, Koshland, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709263/
https://www.ncbi.nlm.nih.gov/pubmed/26583750
http://dx.doi.org/10.7554/eLife.11315