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A dynamic RNA loop in an IRES affects multiple steps of elongation factor-mediated translation initiation

Internal ribosome entry sites (IRESs) are powerful model systems to understand how the translation machinery can be manipulated by structured RNAs and for exploring inherent features of ribosome function. The intergenic region (IGR) IRESs from the Dicistroviridae family of viruses are structured RNA...

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Detalles Bibliográficos
Autores principales: Ruehle, Marisa D, Zhang, Haibo, Sheridan, Ryan M, Mitra, Somdeb, Chen, Yuanwei, Gonzalez, Ruben L, Cooperman, Barry S, Kieft, Jeffrey S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709265/
https://www.ncbi.nlm.nih.gov/pubmed/26523395
http://dx.doi.org/10.7554/eLife.08146