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A dynamic RNA loop in an IRES affects multiple steps of elongation factor-mediated translation initiation
Internal ribosome entry sites (IRESs) are powerful model systems to understand how the translation machinery can be manipulated by structured RNAs and for exploring inherent features of ribosome function. The intergenic region (IGR) IRESs from the Dicistroviridae family of viruses are structured RNA...
Autores principales: | Ruehle, Marisa D, Zhang, Haibo, Sheridan, Ryan M, Mitra, Somdeb, Chen, Yuanwei, Gonzalez, Ruben L, Cooperman, Barry S, Kieft, Jeffrey S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709265/ https://www.ncbi.nlm.nih.gov/pubmed/26523395 http://dx.doi.org/10.7554/eLife.08146 |
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