De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly

Vertebrate centrioles normally propagate through duplication, but in the absence of preexisting centrioles, de novo synthesis can occur. Consistently, centriole formation is thought to strictly rely on self-assembly, involving self-oligomerization of the centriolar protein SAS-6. Here, through recon...

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Detalles Bibliográficos
Autores principales: Wang, Won-Jing, Acehan, Devrim, Kao, Chien-Han, Jane, Wann-Neng, Uryu, Kunihiro, Tsou, Meng-Fu Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709270/
https://www.ncbi.nlm.nih.gov/pubmed/26609813
http://dx.doi.org/10.7554/eLife.10586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709270/
https://www.ncbi.nlm.nih.gov/pubmed/26609813
http://dx.doi.org/10.7554/eLife.10586

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