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Structural homology guided alignment of cysteine rich proteins

BACKGROUND: Cysteine rich protein families are notoriously difficult to align due to low sequence identity and frequent insertions and deletions. RESULTS: Here we present an alignment method that ensures homologous cysteines align by assigning a unique 10 amino acid barcode to those identified as st...

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Detalles Bibliográficos
Autores principales: Shafee, Thomas M. A., Robinson, Andrew J., van der Weerden, Nicole, Anderson, Marilyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709342/
https://www.ncbi.nlm.nih.gov/pubmed/26788439
http://dx.doi.org/10.1186/s40064-015-1609-z