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Structural homology guided alignment of cysteine rich proteins
BACKGROUND: Cysteine rich protein families are notoriously difficult to align due to low sequence identity and frequent insertions and deletions. RESULTS: Here we present an alignment method that ensures homologous cysteines align by assigning a unique 10 amino acid barcode to those identified as st...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709342/ https://www.ncbi.nlm.nih.gov/pubmed/26788439 http://dx.doi.org/10.1186/s40064-015-1609-z |